A431 cells were subjected to SDS PAGE followed by western blot with FNab02799(EPCAM antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab02799(EPCAM antibody) at dilution of 1:100
Immunofluorescent analysis of A431 cells using FNab02799 ( EPCAM Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Background
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.